St Ann Blackfriars was a church in the City of London, in what is now Ireland Yard in the ward of Farringdon Within. The church began as a medieval parish chapel, dedicated to St Ann, within the church of the Dominicans. The new parish church was established in the 16th century to serve the inhabitants of the precincts of the former Dominican monastery, following its dissolution under King Henry VIII. It was near the Blackfriars Theatre, a fact which displeased its congregation. It was destroyed in the Great Fire of London of 1666.